Oxford Handbook of Critical Care

Requirements: 2.1+
Overview: This Oxford Handbook of Critical Care, Third Edition is developed by MedHand Mobile Libraries.

 The fully revised, third edition of this bestselling Handbook describes best practice of critical care in a succinct, concise and clinically-orientated way. Covering the principles of general management, it includes therapeutic and monitoring devices, specific disorders of organ systems, as well as detailed information on drugs and fluids.

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MedCalc 3000 Complete

Requirements: Android OS v2.2+
Overview: MedCalc 3000 Complete: Your answer for medical calculation

MedCalc 3000 is the most popular and comprehensive Medical Calculator system on the web. MedCalc 3000 has been highly acclaimed, reviewed and tested over the last 11 years. As a trusted resource it has been integrated into many prestigious websites for Medical Education, Medical Literature, Pharmacology, Nursing and more. Now you can put this invaluable resource in the palm of your hand!

MedCalc 3000 encompasses over 520 pertinent medical equations, clinical criteria sets, decision tree tools and dose/unit converters used every day by clinicians, educators, nurses, pharmacologists and students of all types. With the growing emphasis on Evidence-Based Medicine, there has never been a greater need for a system such as MedCalc 3000.

MedCalc 3000 Complete mirrors the web based resource MedCalc3000.com There you can see the complete list of components you’ll have in the Android Edition.


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Dorland's Illustrated Medical

Requirements: 2.0 and up
Overview: Dorland's medical - 120 000 entries, 1500 images, 35000 audio pronunciations

Dorland's medical - 120 000 entries, 1500 images, 35000 audio pronunciations

The first and last word in medicine for over 110 years! Thoroughly updated, this user-friendly reference, trusted for more than a century by healthcare personnel at every professional level, allows you to grasp the meanings of all medical terms in current usage. Understand and correctly use all the latest terminology in today’s ever-evolving medical field with the 32nd Edition of the comprehensive, highly respected Dorland’s Illustrated Medical Dictionary!

Key Features:

* Enhance your understanding of all the current medical terminology in your field by relying on the most comprehensive and highly respected medical dictionary, bringing you more than 120,000 well-defined entries and 1500 clear illustrations.
* Listen to 35,000 audio pronunciations.

* New to This Edition:
* Make sure you're familiar with the very latest medical terms used today with more than 5,500 new entries drawn from current sources.
* Complement your understanding of new words and ideas in medicine with 500 new illustrations .
* Get more information in a smaller amount of space as the revised entry format includes related parts of speech.


The MSDict Dictionary Format

The Dorland's Illustrated Medical Dictionary is here presented in MSDict electronic format. MSDict offers best experience in mobile reference and is available for any handheld platform.

* Quick dynamic search of words while you type
* Transcriptions facilitating pronunciation
* Hyperlinks between different related words
* History to see the last 50 words you have looked up
* Support for memory cards
* Filters to help you locate the word you are searching for:
* Fuzzy filter- used when you are not sure of the correct spelling of a word
* Keyword-used to locate the instances of a key word within other compound words
* Wild card - "?" and "*" replace a letter and group of letters in words
* Fast article scrolling
* Ability to have dictionary Word of the day as a widget on the phone home screen
* Ability to search words in the installed dictionaries through the standard phone search feature

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Pedi Safe Medications v3.3

Requirements: Android 1.6+
Overview: Pediatric Emergency Guide for medications, airway equipment, and Broselow Colors

Pediatric Emergency Guide for medications, airway equipment, and Broselow Colors

Features
• Pediatric & Adult Weight-Based Doses
• Broselow Colors Help Identify Weight
• Airway Equipment Selection & Size
• Normal Vitals Signs for Pediatrics
• ACLS & PALS Emergency Medications
• Simplify the Medication Delivery System

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Sanford Guide v2.02

Requirements: Android 1.6+
Overview: The Sanford Guide is the essential resource for healthcare professionals who care for patients with infectious diseases. The Sanford Guide to Antimicrobial Therapy application provides fast, convenient access to critical information on treatment of infectious diseases, for timely, effective decisions at the point of care.

The Sanford Guide is the essential resource for healthcare professionals who care for patients with infectious diseases. The Sanford Guide to Antimicrobial Therapy application provides fast, convenient access to critical information on treatment of infectious diseases, for timely, effective decisions at the point of care.

Always a pocket guide, still a pocket guide. Portability has been a hallmark of The Sanford Guide for over 40 years. The Sanford Guide to Antimicrobial Therapy application extends that portability to Android devices. The most trusted infectious diseases treatment resource in print now presents the same comprehensive, treatment- focused coverage of infectious diseases and clinical conditions, anti-infective drug information, therapeutic adjuncts and comparative spectra of activity in a clean, uncluttered, device-optimized interface. Based on the Sanford Guide Web Edition, the application features expanded coverage of topics compared to the print edition.

Other than for the initial download and to receive updates, the application may be used fully without the need for connectivity. Maximum screen space is devoted to the display of content by limiting buttons to those considered to be most essential: Home, Back and Search. All buttons are located on the application menu bar. The Index is activated by the search button on the application menu bar. The same button also hides the keyboard for full screen display of Index topics. For more about the application and the Sanford Guide, use the Info button on the launch screen.

Content queries are begun on the launch screen using a searchable Index or four Rapid Reference categories. Diseases and Clinical Conditions are organized by type (bacterial, fungal, mycobacterial, parasitic and viral). Bacterial diseases are further organized by site of infection and organism. Drug Information is similarly organized by type. Therapeutic Adjuncts include post-exposure antimicrobial prophylaxis (e.g., hepatitis, HIV, rabies), as well as preventative prophylaxis for surgical procedures and post-transplants. Comparison Tables include activity spectra tables for bacteria, fungi and viruses. These tables are color-coded for ease of use.

Extensive internal links provide efficient navigation to related content. For instance, drug regimens on disease pages are linked to corresponding pages for each drug containing comprehensive information on usage, dosing, adverse effects, activity, pharmacology, pharmacodynamics and drug-drug interactions. Broad topics such as meningitis and pneumonia include Overview pages with an outline and links to all sub-topics for that disease.

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mediafire

30% of oropharyngeal cancers worldwide are related to HPV infection, linked to sexual practices such as oral sex

In WHO press release on 18 July 2013, A new study by the International Agency for Research on Cancer (IARC), in partnership with Costa Rican investigators and the United States National Cancer Institute (NCI), shows for the first time that the vaccine against human papillomavirus (HPV) types 16 and 18, which is used to prevent cervical cancer, also provides strong protection against oral HPV infections, known to be associated with cancer of the oropharynx and tonsils.

The study, conducted in Costa Rica and published in the journal PLOS ONE, was initially designed to evaluate the vaccine’s efficacy against cervical cancer. It later included evaluation of the vaccine’s efficacy at other anatomical sites, including the oral cavity, where researchers established that the vaccine reduces oral infections with HPV 16 and 18 by more than 90%.

HPV is better known for causing cervical cancer, which is the third most common cancer in women worldwide, with an estimated 530 000 new cases and 275 000 deaths in 2008. HPV types 16 and 18 are also associated with cancers in a variety of other locations, including the vulva, vagina, penis, anus, and oropharynx. The estimated number of new cases of cancer of the oropharynx (including the tonsils and the base of the tongue) is approximately 85 000 per year in both sexes worldwide, and men are 4 times more likely than women to be affected.4 However, the incidence of oropharyngeal cancer has increased significantly in recent years in the USA and Europe, particularly among men and in young people.

According to a recent study in the USA, over the past 20 years, the rate of HPV detection in oropharyngeal tumour specimens increased from 16% to 70%.

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Osteoporosis Management Guidelines Updated by The National Osteoporosis Guideline Group (NOGG)

The National Osteoporosis Guideline Group (NOGG) has updated its 2009 guidelines on the diagnosis and management of osteoporosis in postmenopausal women and men at least 50 years of age in the United Kingdom. The new recommendations were published online June 17 in Maturitas.

"Since [2009] there has been a number of advances in the field, particularly with respect to glucocorticoid-induced osteoporosis, the role of calcium and vitamin D therapy, and the benefits and risks of long-term bisphosphonate therapy," write J. Compston, MD, from the University of Cambridge School of Clinical Medicine, United Kingdom, and colleagues from the NOGG. "In addition new pharmacological interventions have been approved for the prevention of glucocorticoid-induced osteoporosis and the management of osteoporosis in postmenopausal women and men at increased risk."


Selected Highlights of the 2013 Guidelines

• Pharmacotherapies shown to lower the risk for vertebral fracture (and for hip fracture in some cases) include bisphosphonates, denosumab, parathyroid hormone peptides, raloxifene, and strontium ranelate.
• Generic alendronate is usually first-line treatment because of its broad spectrum of antifracture efficacy and low cost.
• Ibandronate, risedronate, zoledronic acid, denosumab, raloxifene, or strontium ranelate may be appropriate therapy when alendronate is contraindicated or poorly tolerated.
• Because of the high cost, parathyroid hormone peptides should be used only for patients at very high risk, especially for vertebral fractures.
• Postmenopausal women may benefit from calcitriol, etidronate, and hormone replacement therapy.
• Approved treatments for men at increased fracture risk are alendronate, risedronate, zoledronic acid, and teriparatide.
• Patients at increased risk for fracture should start alendronate or other bone-protective treatment at the onset of glucocorticoid therapy.
• For postmenopausal women, approved pharmacotherapy for prevention and treatment of glucocorticoid-induced osteoporosis includes alendronate, etidronate, and risedronate; approved treatment options in both sexes are teriparatide and zoledronic acid.
• Calcium and vitamin D supplementation is widely recommended for older persons who are housebound or live in residential or nursing homes and is often recommended as an adjunct to other treatments for osteoporosis.
• Potential adverse cardiovascular effects of calcium supplementation are controversial, but it may be prudent to increase dietary calcium intake and use vitamin D alone rather than using both calcium and vitamin D supplementation.
• Withdrawal of bisphosphonate treatment is associated with decreases in bone mineral density (BMD) and bone turnover after 2 to 3 years for alendronate and 1 to 2 years for ibandronate and risedronate.
• Continuation of bisphosphonates without the need for further evaluation is recommended for high-risk individuals. When bisphosphonates are continued, treatment review, including renal function evaluation, is needed every 5 years.
• If bisphosphonates are discontinued, fracture risk should be re-evaluated after every new fracture, or after 2 years if no new fracture occurs.
• After 3 years of zoledronic acid treatment, the benefits on BMD density persist for at least another 3 years after discontinuation. Most patients should stop treatment after 3 years, and their physician should review the need for continuation of therapy 3 years later.
• Persons with a previous vertebral fracture or a pretreatment hip BMD T-score of −2.5 SD or less may be at increased risk for vertebral fracture if zoledronic acid is discontinued.

"At present there is no universally accepted policy for population screening in the UK to identify individuals with osteoporosis or those at high risk of fracture," the guideline authors write. "Patients are identified opportunistically using a case finding strategy on the finding of a previous fragility fracture or the presence of significant [clinical risk factors]. Some of these risk factors act independently of BMD to increase fracture risk whereas others increase fracture risk through their association with low BMD (e.g. some of the secondary causes of osteoporosis)."

An independent expert related the new UK guidelines to those used in Canada, released and published in 2010. "As with the current Canadian guidelines, the UK guidelines generally recommend fracture risk assessment in advance of making treatment recommendations," said Joanna Sale, PhD, associate scientist, Mobility Program Clinical Research Unit, St. Michael's Hospital, Toronto, Ontario, Canada, in an interview with Medscape Medical News.

"The recommendations in the guideline are intended to aid management decisions but do not replace the need for clinical judgment in the care of individuals in clinical practice," the group contributors conclude.

Malaysia's Clinical Guidance on Management of Osteoporosis 2012 can be found here.

Article reposted from Medscape.




Maturitas. Published online June 17, 2013. Full text